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High-yield PLAB 1 topics: what to revise first

A study order for PLAB 1 based on the GMC content map and the UK guidelines that underlie common clinical questions.

7 minute read · reviewed 24 October 2026

No one outside the GMC knows how often each topic appears, so be wary of “guaranteed” lists. A sensible way to prioritise is to start with common, serious and safety-critical conditions, then fill gaps from the GMC’s content map.

A practical order

PriorityAreasWhy
1Emergencies: sepsis, anaphylaxis, acute coronary syndromes, stroke, head injury, upper GI bleeding, ABCDE assessmentSafety-critical and tested in every setting
2Common chronic disease: hypertension, diabetes, asthma, COPD, heart failure, CKDFirst-line drugs and monitoring come straight from NICE
3Obstetrics and gynaecology, paediatrics, mental healthLarge areas where many candidates have less UK exposure
4Prescribing and safe practice: BNF, interactions, renal and pregnancy cautionsCommon source of wrong answers
5Ethics, law and professionalism, evidence and statisticsMarks that are quick to gain; see Good Medical Practice

How to revise each topic

  1. Open the current NICE guideline or CKS page.
  2. Write: presentation, key investigation, first-line, second-line, when to refer.
  3. Do 10 questions on it the same week.
  4. Add every missed question to a revision list and revisit it after a week.

The map from topic to guideline is in the UK guidelines to learn. Put the topics into a calendar with a study plan.

Related guides

General education, reviewed 24 October 2026. Guidance changes: confirm with the official sources. Not medical, legal or immigration advice.