Insights into early-onset colorectal cancer from a single-nucleus RNA-seq atlas of colorectal cancer across the age continuum

Synopsis

Nature Medicine, Published online: 29 October 2026; doi:10.1038/s41591-026-04721-y A high-resolution snRNA-seq atlas of 189 colorectal tumors from patients aged 20–90+ years uncovers age-associated features of colorectal cancer.

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