Metabolic heterogeneity of obesity

Synopsis

Nature Medicine, Published online: 27 October 2026; doi:10.1038/s41591-026-04718-7 This Review examines the cellular, organ-level and whole-body differences between metabolically healthy and metabolically unhealthy obesity, as well as variations in response to weight loss—with the goal of improving strategies for preventing and treating obesity-related metabolic disorders.

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